atonal is a proneural gene for a subset of olfactory sense organs in Drosophila
نویسندگان
چکیده
منابع مشابه
amos, a Proneural Gene for Drosophila Olfactory Sense Organs that Is Regulated by lozenge
In a variety of organisms, early neurogenesis requires the function of basic-helix-loop-helix (bHLH) transcription factors. For the Drosophila PNS, such transcription factors are encoded by the proneural genes (atonal and the achaete-scute complex, AS-C). We have identified a proneural gene, amos, that has strong similarity with atonal in its bHLH domain. We present evidence that amos is requir...
متن کاملRole of the proneural gene, atonal, in formation of Drosophila chordotonal organs and photoreceptors.
The Drosophila gene atonal encodes a basic helix-loop-helix protein similar to those encoded by the proneural genes of the achaete-scute complex (AS-C). The AS-C are required in the Drosophila PNS for the selection of neural precursors of external sense organs. We have isolated mutants of atonal, which reveal that this gene encodes the proneural gene for chordotonal organs and photoreceptors. I...
متن کاملSense organ identity in the Drosophila antenna is specified by the expression of the proneural gene atonal
We have shown that the basic helix-loop-helix transcription factor Atonal is sufficient for specification of one of the three subsets of olfactory sense organs on the Drosophila antenna. Misexpression of Atonal in all sensory precursors in the antennal disc results in their conversion to coeloconic sensilla. The mechanism by which specific sense organ fate is triggered remains unclear. We have ...
متن کاملatonal Regulates Neurite Arborization but Does Not Act as a Proneural Gene in the Drosophila Brain
Drosophila atonal (ato) is the proneural gene of the chordotonal organs (CHOs) in the peripheral nervous system (PNS) and the larval and adult photoreceptor organs. Here, we show that ato is expressed at multiple stages during the development of a lineage of central brain neurons that innervate the optic lobes and are required for eclosion. A novel fate mapping approach shows that ato is expres...
متن کاملThe formation of sense organs in Drosophila: a logical approach.
The genetic analysis of development has revealed the importance of small sets of interacting genes in most morphogenetic processes. The results of gene interactions have so far been examined intuitively. This approach is largely sufficient when one deals with simple interactions, a feedback circuit for example. As more components become involved, however, it is difficult to make sure that the i...
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ژورنال
عنوان ژورنال: Genes to Cells
سال: 1997
ISSN: 1356-9597,1365-2443
DOI: 10.1046/j.1365-2443.1997.d01-312.x